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He found that burgers can be quite safely cooked with care.2 But what changed the direction of his research was an entirely original discovery, separate from what his paper set out to find. This discovery has shaped his career since and may well, in the years to come, help thousands, indeed millions, of people improve their health. What he discovered was that something in hamburger has a “mutagenic free access inhibitory” effect. That is, something in meat seemed free access to counteract the bad effects of these mutagens, indeed was an anti-mutagen. In his research, free access Pariza used a popular scientific test called the Ames Test, named for a scientist at the University of California at Berkeley. This test is still used today for its simplicity by numerous scientists. The test requires enzymes form rat livers stimulated with certain chemicals. Scientists put these enzymes and the possible mutagen onto bacteria. They observe the bacteria in a microscope to see if they have mutated.
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