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1995 May;61(5):1052-7. Links Increasing the dietary polyunsaturated fat content alters whole-body utilization of 16:0 ldl cholesterol and 10:0.Clandinin MT, Wang LC, Rajotte RV, French ldl cholesterol MA, Goh YK, Kielo ES.Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.Six healthy adult males were fed four different diets to determine the effects of the quantity of fat (30% or ldl cholesterol 40% of energy as fat) and type of fat (polyunsaturated or saturated) on utilization of fatty acids. Each diet was fed for 15 d. The ratio of dietary polyunsaturated to saturated fat (P:S) was formulated at either 0.2 or 1.0 at both fat intakes. Subjects provided breath tests to measure background 13C and response to [1-13C]10:0 and [1-13C]16:0 fed with a test meal. Increasing the P:S increased whole-body oxidation of labeled 10:0 by 30% after consumption of both low- and high-fat diets.
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