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nuclear age history, milk, living, health articles, hewlettpackard, bikini atoll, cooking hints, copystar, omega 3 fatty acids, vitamins, burn, loss of weight, electrical impedance, pentabasol, hyeana, medline, chubby, eggs, | However, we first must continue with studies to determine the safety of leptin as a possible therapy." The researchers previously published a study documenting heatzone a 30 percent weight loss in genetically obese mice given daily injections of leptin for two weeks. While receiving leptin, the mice ate less and increased heatzone their use of energy. The instructions to make leptin are found in the obese (ob) gene. Friedman and his colleagues cloned the ob gene in mice in 1994 and reported in July 1995 heatzone that it makes leptin, which is produced only in fat and then is released into the blood stream. The findings reported in the Nature Medicine article stem from studies in people, mice and rats by scientists at Rockefeller, HHMI, Brookwood Biomedical Medical Center, Cedar-Siani Medical Center, and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). |
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"Some obese people may make leptin at a greater rate health articles to compensate for a faulty signaling process or action," Friedman health articles says. "If resistance to leptin is partial, rather than complete, more leptin may be required for action." In addition, obesity may occur if genetic or environmental factors affect body chemistry after leptin acts, notes lead author Margherita Maffei, Ph.D., postdoctoral health articles associate in Friedman's laboratory. Leptin's signaling ability may also help explain the high rates of regaining weight found among dieters, the investigators report. "After dieting, the levels of leptin drop, suggesting that less leptin is made and available to signal the brain," Friedman says. "This reduction may contribute to increased hunger and slower metabolism. If this is true, leptin therapy may help people maintain weight loss after dieting. |
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