T4 deiodination in liver, eating quality beef

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T4 deiodination in liver, contrary to the T4 clearance rate, depends on fat content of diet and not of body. The thyroidal radioiodine uptake and PBI-131-values in some weight groups of HFD-rats were significantly higher than in some LFD-weight-groups, but a dependence of the beef thyroidal activity from beef fat content of diet or of body was beef not clearly evident. The results indicate however, that the thyroidal activity is likely not responsible for the increase of liver deiodinase activity after high fat diet. The apparent discrepancy between the results of higher liver T4 deiodination and equal or lower T4 clearance rate or equal T3 serum concentrations is discussed.PMID: 6159208 [PubMed - indexed for MEDLINE]  Display  Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1
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