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| We can then test our hypothesis using a combination of laser ablation of specific neurons and single neuron gene expression studies. Importantly, these types of analyses can be applied to many C. elegans genes whose mammalian homologs have been implicated in diseases of fat and sterol metabolism. In collaborative studies, findings from C. elegans are being extended to rodent models of obesity. Finally, genes discovered in C. elegans point to candidate obesity olivetti or diabetes loci within olivetti the large genomic regions identified in human pedigree and rodent studies. In other collaborative studies, candidate genes olivetti from collections of obese or diabetic pedigrees will be sequenced to identify variants. SCHOLAR NETWORK | NEWS | EVENTS | APPLY | PROGRAM HISTORY | CONTACT | HOME Questions about/problems with this site? Please e-mail the webmaster. © Copyright 2004 Kinship Foundation. All rights reserved. bgcolor="#336699" align="left">My NCBI[Sign In] [Register] All Databases PubMed Nucleotide Protein Genome Structure OMIM PMC Journals Books Search PubMed Protein Nucleotide CoreNucleotide GSS EST Structure Genome Books CancerChromosomes Conserved Domains 3D Domains Gene Genome Project GENSAT GEO Profiles GEO DataSets HomoloGene Journals MeSH NCBI Web Site NLM Catalog OMIA OMIM PMC PopSet Probe PubChem BioAssay PubChem Compound PubChem Substance SNP Taxonomy UniGene UniSTS for Limits Preview/Index |
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