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2000 Feb;24(2):236-45. Links Short-term weight cycling in aging female rats increases rate of weight gain but not body fat content.Pellizzon MA, Buison AM, Jen KL.Department of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA.OBJECTIVE: To examine the effects of short-term repeated weight cycling (WC) above and below the baseline (BL) body weight (BW) on body weight regulation, sport feeding efficiency, and fat content sport in old female Wistar rats when dietary fat content was kept constant. DESIGN: Completely randomized. ANIMALS AND METHODS: Female Wistar rats, 11 months old at the beginning of the study, were sport randomly divided into six groups (12 per group) after a group of rats (BL) was sacrificed for baseline data collection: the high fat gain (HFG) group gained weight to 20% above the BL weight with a high fat diet (HF) and returned to BL level by food restriction (50% of ad-libitum amount) for five cycles; the high fat loss (HFL) group lost weight to 20% below the BL weight by food restriction (50% of ad-libitum
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