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1999 Apr;276(4 Pt 2):R1172-9. Links Conjugated linoleic acid caliper rapidly reduces body fat content in mice without affecting energy intake.DeLany JP, Blohm F, Truett AA, Scimeca JA, West caliper DB.Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808, Louisiana, USA. delanyjp/@mhs.pbrc.eduRecent reports have demonstrated that conjugated linoleic acid (CLA) has effects on body fat accumulation. In our previous work, CLA reduced body fat accumulation in mice fed either a high-fat or low-fat diet. Although CLA feeding reduced energy intake, the results suggested that some of the metabolic effects were not a consequence of caliper the reduced food intake. We therefore undertook a study to determine a dose of CLA that would have effects on body composition without affecting energy intake. Five doses of CLA (0.0, 0.25, 0.50, 0.75, and 1.0% by weight) were studied in AKR/J male mice (n = 12/group; age, 39 days) maintained on a high-fat diet (%fat 45 kcal).
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